SGLT inhibitors in cancer therapy

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Inhibition of cell growth and induction of apoptosis by HDAC4/5 inhibition using LMK-235 has been reported for different malignancy cell lines as well as chemoresistant malignancy cell lines [13,23,31,35]. practical inhibition of HDAC4/5. Immunocytochemical analysis showed that proliferative activity (phosphohistone…

In keeping with this simple idea, pharmacological DDR1 inhibition with nilotinib, a TK inhibitor currently found in the medical clinic to focus on the BCR\ABL oncogene in chronic myeloid leukaemia, shows a potent anti\metastatic activity in CRC. Impact Our results…

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